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Evidence for a selective and multi-step model of T cell differentiation: CD4+CD8low thymocytes selected by a transgenic T cell receptor on major histocompatibility complex class I molecules

✍ Scribed by Hanspeter Pircher; Pamela S. Ohashi; Richard L. Boyd; Hans Hengartner; Karin Brduscha

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
657 KB
Volume
24
Category
Article
ISSN
0014-2980

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## Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class 11, T cell receptor and CD4 surface molecule densities* We have produced up Tcell receptor (TcR)-transgenic mice and studied MHC-dependent positive selection of T cells