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Molecular basis of α-thalassemia in Sicily

✍ Scribed by Marco Fichera; Angela Spalletta; Flavia Fiorenza; Turi Lombardo; Gino Schilirò; Ryad Tamouza; Claudine Lapouméroulie; Dominique Labie; A. Ragusa


Publisher
Springer
Year
1997
Tongue
English
Weight
201 KB
Volume
99
Category
Article
ISSN
0340-6717

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The molecular basis of β-thalassemia in
✍ A. N. Başak; H. Özçelik; A. Özer; A. Tolun; M. Aksoy; L. Ağaoğlu; F. Ridolfi; L. 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 471 KB

By using oligonucleotide hybridization, restriction endonuclease analysis and direct sequencing of amplified genomic DNA, we have been able to characterize 18 different mutations in the beta-globin genes of 161 beta-thalassemia homozygotes and 107 beta-thalassemia heterozygotes from Turkey (429 beta