Six Algerian patients with beta 0 thalassemia are presented, in addition to the two patients already reported (Godet et al., 1977). Family studies indicate that all the patients had homozygous beta thalassemia characterized by absence of beta globin chain synthesis in peripheral blood. The clinical
✦ LIBER ✦
Genetic heterogeneity of β-thalassemia in southeast sicily
✍ Scribed by Professor G. Schilirò; F. di Gregorio; P. Samperi; E. Mirabile; R. Liang; M. A. Cürük; Z. Ye; T. H. J. Huisman
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 550 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
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## Abstract Thalassemias are a group of genetic hemolytic disorders with varying phenotypes. In this study, the frequency of α globin gene deletions was studied in the β‐thalassemia trait, the mildest form of the disorder. Eleven out of 33 (33%) individuals were positive for α^−3.7 kb^ deletions. N