## Abstract An in vitro model of vascular damage was used to investigate the ability of seeded endothelial cells to resist shear stresses generated in a perfusion circuit. At perfusion rates of 100 ml/min the maximum shear stress reached 16.5 dyn/cm2. At this level the rate of cell detachment from
โฆ LIBER โฆ
Molecular basis of the effects of shear stress on vascular endothelial cells
โ Scribed by Yi-Shuan J. Li; Jason H. Haga; Shu Chien
- Book ID
- 108159275
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 963 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0021-9290
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## Abstract We attempted to clarify the effect of different types of shear stress on endothelial cell (EC) proliferation and survival. Bovine aortic ECs were subjected to either steady laminar, 1 Hz pulsatile, or 1 Hz to and fro shear at 14 dyne/cm^2^. % of BrdU positive EC was 14.3โยฑโ1.6% in stead