Molecular basis for Epstein-Barr virus induced pathogenesis and disease
✍ Scribed by Sample, Clare ;Kieff, Elliott
- Book ID
- 104661108
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 941 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0344-4325
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## Abstract Six cotton‐topped marmoset monkeys (__Sangiunus oedipus__) were inoculated with 10^5^ tranforming units of B95‐8 virus, and two of them developed fatal lymphoproliferative disease. The EBV‐carrying tumor cells from these marmosets had the following characteristics: (I) they were polyclo
## Abstract Epstein–Barr virus (EBV)‐associated B‐cell lymphoproliferative disease may be polyclonal, oligoclonal, or monoclonal. The degree of tumor clonality reflects the disease pathogenesis and may have implications for disease diagnosis, prognosis, and treatment. In this study, specimens of EB