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Molecular association for the design of anti-HIV-1 agents. Conformational study of {3′-azido-3′-deoxythymidine}–{4,5,6,7-tetrahydro-5-methylimidazo-[4,5,1-jk][1,4]benzodiazepin-2(1H)-one} derivatives

✍ Scribed by V.O. Nava-Salgado; R. Martı́nez; M.F. Rubio Arroyo; G.R. Galicia


Book ID
114140947
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
390 KB
Volume
504
Category
Article
ISSN
0166-1280

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NMR spectra and conformational analysis
✍ Farnaz Malik; Mashooda Hassan; Doris Rosenbaum; Helmut Duddeck 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 400 KB

An investigation of the molecular dynamics of substituted 1,3,4,5-tetrahydro-2H-l,Ibenzodiazepin-2-0ne derivatives revealed that these molecules adopt cycloheptadiene-like boat conformations. There is an equilibrium between the quasi-axial and the quasiequatorial conformer in which the quasi-axial c