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From 4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1- jk ](1,4)benzodiazepin-2(1 H )-one (TIBO) to Etravirine (TMC125): Fifteen Years of Research on Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase †

✍ Scribed by De Corte, Bart L.


Book ID
120187709
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
358 KB
Volume
48
Category
Article
ISSN
0022-2623

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✍ Gregory C. Leo; A. Diane Gauthier; Gary W. Caldwell; Michael J. Kukla 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB

## Abstract Proton and carbon NMR chemical shift assignments for (+)‐(__S__)‐4,5,6,7‐tetrahydroimidazo‐9‐chloro‐5‐methyl‐6‐(3‐methylbut‐2‐enyl)imidazo[4,5,1‐__jk__][1,4] benzodiazepin‐2(1__H__)‐thione (TIBO) were made based on 1D and 2D NMR measurements at 9.4 T.