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Molecular assembly and subcellular distribution of ATP-sensitive potassium channel proteins in rat hearts

✍ Scribed by Akihiko Kuniyasu; Kazuyoshi Kaneko; Kohichi Kawahara; Hitoshi Nakayama

Book ID
117105772
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
246 KB
Volume
552
Category
Article
ISSN
0014-5793

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We have used 'caged-ATP' to investigate the kinetic behavior of KATP channels in ventricular cells from rat heart. In whole cells, loaded with 'caged-ATP', an increase of intracellular [ATP] following a UV light flash produced a decrease of KATP channel current that was too slow (tau approximately 3