Molecular aspects of early stages of bre
β
Helene S. Smith; You Lu; Guoren Deng; Olivia Martinez; Sheri Krams; Britt-Marie
π
Article
π
1993
π
John Wiley and Sons
π
English
β 806 KB
It is clear that breast cancer progression is associated with inactivation of a number of different recessive oncogenes. The most widely evaluated tumor suppressor gene, p53, is mutated in approximately 30-50% of sporadic breast cancers. Mutations usually occur early in malignant progression. Loss o