Molecular and crystal structure of 2-acetylmethylene-1-methyl-4{[2,2]-paracyclophan-4′-YL}-1,2,5,6-tetrahydropyridine
✍ Scribed by L. N. Kuleshova; V. N. Khrustalyov; Yu. T. Struchkov; A. T. Soldatenkov; Zh. A. Mamyrbekova; I. A. Bekro; S. A. Soldatova; V. N. Guryshev
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 1996
- Tongue
- English
- Weight
- 703 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-4766
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## Abstract A useful approach for the synthesis of pharmacologically active tetrahydropyridinylbenzimidazoles is described. 2‐Pyridin‐3‐ylbenzimidazoles **3a‐d** have been synthesized by condensation of 3‐pyridinecarbox‐aldehyde **1** with substituted 1,2‐phenylenediamines **2a‐d** following oxidat
A novel method for the synthesis of 1,2,4-trisubstituted-or 1,2,3,4-tetrasubstituted-1,2,5,6-tetrahydropyridine is presented. The process was carried out by the bromomethoxylation of 4-substituted-1,2,5,6-tetrahydropyridines 1 with N-bromosuccinimide (NBS) in methanol, dehydrobromination with 1,8-di