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Molecular and cellular mechanisms governing glucose-dependent insulinotropic polypeptide receptor desensitization

Book ID
116104976
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
107 KB
Volume
64
Category
Article
ISSN
0167-0115

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## Abstract Glucose‐dependent insulinotropic polypeptide (GIP) was initially described to be rapidly regulated by endocrine cells in response to nutrient ingestion, with stimulatory effects on insulin synthesis and release. Previously, we demonstrated a significant up‐regulation of GIP mRNA in the