## Abstract The integration of hepatitis B virus (HBV) DNA in the liver of chronic HBV carriers has been documented extensively. However, the status of the viral genome during acute infection has not been assessed conclusively. While HBV DNA sequences are detected often in serum, liver, and periphe
Molecular Analysis of Hepatitis B Virus DNA in Serum and Peripheral Blood Mononuclear Cells From Hepatitis B Surface Antigen–Negative Cases
✍ Scribed by Marı́a Cabrerizo; Javier Bartolomé; Carlos Caramelo; Guillermina Barril; Vicente Carreño
- Book ID
- 111721286
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 150 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0270-9139
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## Abstract The presence of both hepatitis B virus (HBV) DNA and HBV antigens (HBsAg, HBeAg) was assessed in peripheral blood mononuclear cells (PBMC) from 32 patients chronically infected with HBV. Three different molecular forms of HBV DNA were observed: free monomers (5), high‐molecular‐weight f
In this study, peripheral-blood mononuclear cells from patients with chronic hepatitis B and spontaneous or therapy-induced disappearance of HBsAg were examined for HBV DNA. Samples were evaluated by in situ hybridization and polymerase chain reaction both before and after clearance of HBsAg. By in
## VICENTE CARRENO The presence of hepatitis B virus DNA was studied in peripheral blood mononuclear cell samples from 259 HBsAg carriers (229 anti-hepatitis delta negative, 30 anti-hepatitis delta positive), 16 anti-HBc-positive HBsAg-negative patients and 30 patients without hepatitis B virus ma