The X-linked hypoxanthine-guanine phosphoribosyl-respectively. These data were similar to the reported transferase (hprt) gene is a target of analyses of in values. The mean MFs in the nine colon cancer pavivo mutation frequencies in circulating T-lympho-tients (10.6 { 7.3 1 10 06 ) were not signifi
Molecular analyses of in vivo hypoxanthine-guanine phosphoribosyltransferase mutations in human T-lymphocytes: II. Demonstration of a clonal amplification ofhprt mutant T-lymphocytes in vivo
โ Scribed by Nicklas, J. A. ;O'Neill, J. P. ;Sullivan, L. M. ;Hunter, T. C. ;Allegretta, M. ;Chastenay, B. F. ;Libbus, B. L. ;Albertini, R. J.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1988
- Weight
- 860 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0192-2521
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## Molecular analysis of hypoxanthine-guanine analyzed in more detail by sequencing the gephosphoribosyltransferase (hprt) cDNA from nomic regions flanking the mis-spliced exon. ## 6-thioguanine-resistant T-lymphocytes cloned Base pair substitutions or small deletions causfrom smoking and non-s