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Molecular analyses of in vivo hypoxanthine-guanine phosphoribosyltransferase mutations in human T-lymphocytes: II. Demonstration of a clonal amplification ofhprt mutant T-lymphocytes in vivo

โœ Scribed by Nicklas, J. A. ;O'Neill, J. P. ;Sullivan, L. M. ;Hunter, T. C. ;Allegretta, M. ;Chastenay, B. F. ;Libbus, B. L. ;Albertini, R. J.


Publisher
Wiley (John Wiley & Sons)
Year
1988
Weight
860 KB
Volume
12
Category
Article
ISSN
0192-2521

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## Molecular analysis of hypoxanthine-guanine analyzed in more detail by sequencing the gephosphoribosyltransferase (hprt) cDNA from nomic regions flanking the mis-spliced exon. ## 6-thioguanine-resistant T-lymphocytes cloned Base pair substitutions or small deletions causfrom smoking and non-s