Molecular genetics and chromosomal alter
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William B. Isaacs; G. Steven Bova; Ronald A. Morton; Marion J. G. Bussemakers; J
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Article
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1995
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John Wiley and Sons
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English
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The multistep nature of carcinogenesis has been repeatedly demonstrated for a variety of human cancers. Concomitant mutational activation of genes that promote cellular growth (i.e., oncogenes) and inactivation of genes that normally act to restrict or otherwise regulate growth (i.e., tumor suppress