Molecular aberrations in human systemic lupus erythematosus
โ Scribed by George C. Tsokos; Gary M. Kammer
- Book ID
- 114381912
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 233 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1357-4310
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
FAS/FASL system plays a central role in maintaining peripheral immune tolerance. Human Systematic Lupus Erythematosus (SLE) is a prototypic systemic autoimmune disease characterized by expansion of autoreactive lymphocytes. It remains unclear whether a defective FAS/FASL system is involved in the pa
Major advances in understanding the genetic foundation of systemic lupus erythematosus are in the offing. Genetic association studies suggest multiple effects that include those encoded by the HLA region, the genes for Fcgamma receptors and other genes such as that for the mannose-binding protein. G