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MODY in Iceland is associated with mutations in HNF-1α and a novel mutation in NeuroD1

✍ Scribed by S. Y. Kristinsson; E. T. Thorolfsdottir; B. Talseth; E. Steingrimsson; A. V. Thorsson; T. Helgason; A. B. Hreidarsson; R. Arngrimsson


Book ID
105822523
Publisher
Springer
Year
2001
Tongue
English
Weight
95 KB
Volume
44
Category
Article
ISSN
0012-186X

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Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including