Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including
✦ LIBER ✦
Mutations in GCK and HNF-1α explain the majority of cases with clinical diagnosis of MODY in Spain
✍ Scribed by Itziar Estalella; Itxaso Rica; Guiomar Perez De Nanclares; Jose Ramon Bilbao; Jose Antonio Vazquez; Jose Ignacio San Pedro; Maria Angeles Busturia; Luis Castaño; Spanish MODY Group
- Book ID
- 108703809
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 156 KB
- Volume
- 0
- Category
- Article
- ISSN
- 0300-0664
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
GCK and HNF1A mutations in Canadian fami
✍
Henian Cao; Sanam Shorey; John Robinson; Daniel L. Metzger; Laura Stewart; Eliza
📂
Article
📅
2002
🏛
John Wiley and Sons
🌐
English
⚖ 28 KB
👁 2 views
Routine mutation screening of HNF-1α and
✍
Boutin, P.; Vasseur, F.; Samson, C.; Wahl, C.; Froguel, P.
📂
Article
📅
2001
🏛
Springer
🌐
English
⚖ 85 KB
Identification of novel GCK and HNF1A/TC
✍
Dalia Toaima; Andrea Näke; Jutta Wendenburg; Kirsten Praedicow; Julia Rohayem; K
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
English
⚖ 74 KB
👁 2 views
Maturity-onset diabetes of the young is a genetically heterogenous autosomal dominant form of diabetes mellitus, characterized by an early age at onset and a primary defect in beta-cell function. Forty families with a clinical presentation suggestive of MODY were screened for the most common MODY su
Co-inheritance of HNF1a and GCK mutation
✍
López-Garrido, M. P.; Herranz-Antolín, S.; Alija-Merillas, M. J.; Giralt, P.; Es
📂
Article
📅
2013
🏛
John Wiley and Sons
🌐
English
⚖ 255 KB
Half of Clinically Defined Maturity-Onse
✍
Johansen, A.; Ek, J.; Mortensen, H. B.; Pedersen, O.; Hansen, T.
📂
Article
📅
2005
🏛
Endocrine Society
🌐
English
⚖ 107 KB
The spectrum of HNF1A gene mutations in
✍
Tatsi, Christina; Kanaka-Gantenbein, Christina; Vazeou-Gerassimidi, Adriani; Chr
📂
Article
📅
2013
🏛
John Wiley and Sons
🌐
English
⚖ 533 KB