Modulation of transcription in rat liver
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Shah, G. M. ;Bhattacharya, R. K.
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Article
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1992
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John Wiley and Sons
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English
β 423 KB
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## Abstract Treatment of isolated rat liver nuclei with 7Ξ², 8Ξ±βdihydroxyβ9Ξ±, 10Ξ±βepoxyβ7, 8, 9, 10βtetrahyβdrobenzo[a]pyrene, the ultimate carcinogenic metabolite of benzo[a]pyrene, resulted in inhibition of transcription as measured by radioactive precursor incorporation into RNA. The mechanism of