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Modulation of transcription in rat liver by benzo[a]pyrene

✍ Scribed by Shah, G.M.; Bhattacharya, R.K.


Book ID
122609172
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
561 KB
Volume
35
Category
Article
ISSN
0304-3835

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Modulation of transcription in rat liver
✍ Shah, G. M. ;Bhattacharya, R. K. πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 423 KB πŸ‘ 1 views

## Abstract Treatment of isolated rat liver nuclei with 7Ξ², 8α‐dihydroxy‐9Ξ±, 10α‐epoxy‐7, 8, 9, 10‐tetrahy‐drobenzo[a]pyrene, the ultimate carcinogenic metabolite of benzo[a]pyrene, resulted in inhibition of transcription as measured by radioactive precursor incorporation into RNA. The mechanism of