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Modulation of thymidine phosphorylase by neoadjuvant chemotherapy in primary breast cancer

✍ Scribed by Toi, M; Bando, H; Horiguchi, S; Takada, M; Kataoka, A; Ueno, T; Saji, S; Muta, M; Funata, N; Ohno, S

Book ID
109998077
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
143 KB
Volume
90
Category
Article
ISSN
0007-0920

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## Abstract Thymidine phosphorylase (TP), also known as β€œplatelet‐derived endothelial cell growth factor” (PD‐ECGF), is an enzyme, which is upregulated in a wide variety of solid tumors including breast and colorectal cancers. TP promotes tumor growth and metastasis by preventing apoptosis and indu