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Modulation of the Ryanodine Receptor and Intracellular Calcium

✍ Scribed by Zalk, Ran; Lehnart, Stephan E.; Marks, Andrew R.

Book ID: 118257671
Publisher: Annual Reviews
Year: 2007
Tongue: English
Weight: 475 KB
Volume: 76
Category: Article
ISSN: 0066-4154
DOI: 10.1146/annurev.biochem.76.053105.094237

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## Abstract Changes in intracellular Ca^2+^ concentration were monitored in cultured cortical astrocytes challenged with ryanodine and ATP. Ryanodine elicited a modest, in comparison to ATP, increase in cytosolic Ca^2+^ concentration in approximately 60% of the cell fields examined. This effect was