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Modulation of the mutagenic effects of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) in bacteria with rat-liver 9000 × g supernatant or monolayers of rat hepatocytes as an activation system

✍ Scribed by Jørn A. Holme; Gunnar Brunborg; Jan Alexander; Bente Trygg; Christine Bjørnstad


Book ID
113193460
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
870 KB
Volume
197
Category
Article
ISSN
0027-5107

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Mutagenic activation of 2-amino-3-methyl
✍ Jørna A. Holme; Jan Alexander; Erik Dybing 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 669 KB

The mutagenic activity of the pyrolysis products 2-amino-3-methylimidazo [4,5-J'\_~quinoline and 2-amino-3, 4-dimethylimidazo[4,5-fJ-quinoline in Salmonella typhimurium TA98 using rat intestinal and renal subcellular fractions as activation systems was approximately 1 and 5 revertants per nmol, resp