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Modulation of the kynurenine pathway with selective enzyme inhibitors: Focus on biochemistry and behavior

✍ Scribed by Chiarugi, A.; Carpenedo, R.; Moroni, F.


Book ID
123469160
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
179 KB
Volume
31
Category
Article
ISSN
1043-6618

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**The cover picture shows** one branch of the kynurenine pathway of tryptophan metabolism, which is mainly localized in astrocytes. One key metabolite, kynurenic acid (KYNA), is transported in the extracellular space, where it modulates synaptically localized Ξ±7β€…nicotinic acetylcholine receptors and