Activation of the Ha-ras proto-oncogene, but not the Ki-ras or N-ras genes, has been found in mammary gland carcinomas induced in female rats by a single dose of methylnitrosourea (MNU). Here we show that a 10-kb restriction fragment containing the Ha-ras gene was extensively methylated by MNU in DN
โฆ LIBER โฆ
Modulation of the human Ha--1 oncogene expression by DNA methylation
โ Scribed by Pierotti, Marco A.; Borrello, Maria G.; Bongarzone, Italia; R. Cattadori Rosangela Donghi, Maria; Mondellini, Piera; Traversari, Catia; Della Porta, Giuseppe
- Book ID
- 122817243
- Publisher
- Elsevier Science
- Year
- 1987
- Weight
- 248 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0277-5379
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