Modulation of phenotypic and functional properties of human peripheral blood monocytes by interleukin-4 (IL-4)
✍ Scribed by A. A. Velde; B. A. Yard; J. P. G. Klomp; J. E. Vries; C. G. Figdor
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1989
- Tongue
- English
- Weight
- 102 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1420-908X
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## Abstract The growth‐inhibitory effect of interleukin‐4 (IL‐4) was investigated in a panel of 7 human colorectal‐carcinoma cell lines. In 5 cell lines (HT29, WiDr, LS41 IN, LS513, LS1034) a dosedependent reduction of proliferation was documented. At 100 U/ml, IL‐4 inhibited thymidine incorporatio