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Modulation of paraoxonase (PON1) activity

โœ Scribed by Lucio G. Costa; Annabella Vitalone; Toby B. Cole; Clement E. Furlong


Book ID
113487395
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
230 KB
Volume
69
Category
Article
ISSN
0006-2952

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The active site of human paraoxonase (PO
โœ Denis Josse; Oksana Lockridge; Weihua Xie; Cynthia F. Bartels; Lawrence M. Schop ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 83 KB

Ideally we would like to treat people exposed to nerve agents with an enzyme that rapidly destroys nerve agents. The enzymes considered for such a role include human butyrylcholinesterase (BChE), acetylcholinesterase (AChE), carboxylesterase and paraoxonase (PON1). Success has been achieved in endow