Modulation of Non-N-Methyl-D-Aspartate Receptors in Cultured Cerebellar Granule Cells
β Scribed by Vittorio Gallo; Claudio Giovannini; Giulio Levi
- Book ID
- 111175489
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 726 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3042
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π SIMILAR VOLUMES
The effect of potassium depolarization and N-methyl-D-aspartate (NMDA) on the activity of aspartate aminotransferase (AAT; EC 2.6.1.1), an enzyme suggested to be involved in neurotransmitter glutamate synthesis, was studied in cultured cerebellar granule neurons. Both KCI and NMDA increased AAT acti
The effect of nicotine on basal and electrically evoked (20 Hz for 20 sec) [(3)H]D-aspartate efflux (assumed as an index of transmitter release) was studied in rat cerebellar granule primary cultures. Nicotine (10-100 nM) increased the basal efflux two to three times and concentration-dependently en