Endogenous γ-l-glutamylglutamate is a partial agonist at the N-methyl-d-aspartate receptors in cultured cerebellar granule cells

Long-term exposure to dieldrin reduces γ

Long-term exposure to dieldrin reduces γ-aminobutyric acid type A and N-methyl-D-aspartate receptor function in primary cultures of mouse cerebellar granule cells

✍ Zoila Babot; M. Teresa Vilaró; Cristina Suñol 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB

The organochlorine pesticide dieldrin is a persistent organic pollutant that accumulates in the fatty tissue of living organisms. In mammals, it antagonizes the GABA(A) receptor, producing convulsions after acute exposure. Although accumulation in human brain has been reported, little is known about