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Modulation of nitric oxide and cytokines production by l-arginine in human gut mucosa

✍ Scribed by Stephane Lecleire; Moise Coeffier; Jonathan Leblond; Aurelie Hubert; Sabrina Lemoulan; Andre Petit; Philippe Ducrotte; Pierre Dechelotte; Rachel Marion

Book ID
113545008
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
274 KB
Volume
24
Category
Article
ISSN
0261-5614

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Differential regulation by cytokines of
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Reactive nitrogen intermediates, such as nitric oxide (NO), play an important role in host-defense and injury. Human astrocytes released abundant NO upon stimulation with the pro-inflammatory cytokine interleukin (IL)-lp, which was potentiated by interferon (1FN)-y and tumor necrosis factor (TNFI-a.