𝔖 Bobbio Scriptorium
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Modulation of natural killer cell-mediated cytotoxicity by tamoxifen and estradiol

✍ Scribed by Edward Baral; Eva Nagy; Istvan Berczi


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
801 KB
Volume
75
Category
Article
ISSN
0008-543X

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The effect of tamoxifen (TX) and estradiol (E2) on interleukin-2 (IL-2)-activated killer (LAK) cell-mediated cytotoxicity was examined using spleen cells of Fisher 344 rats as the source of effectors and P815 murine mastocytoma cells as targets. Treatment of target cells with either TX or E2 for 4

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## Abstract Natural killer (NK) cells are a class of lymphocytes important in immune resistance to viral and other serious diseases. The cytotoxic function, or β€˜killing activity’ of NK cells has become important in studies of the effects of stress and other psychosocial factors on physical health.