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Modulation of mitogen-induced spleen cell proliferation and the antibody-forming cell response by beta-endorphin in vivo

✍ Scribed by Kusnecov, Alexander W.; Husband, Alan J.; King, Maurice G.; Smith, Roger


Book ID
122379301
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
745 KB
Volume
10
Category
Article
ISSN
0196-9781

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## Abstract The anti‐pan T cell monoclonal antibody OKT3 was administered daily for 2 weeks in four human renal allograft recipients. The antibody induced a dramatic and immediate depletion of peripheral T cells followed by an __in vivo__ antigenic modulation of the OKT3‐defined membrane antigen: a