Modulation of map kinase signaling and growth characteristics by the overexpression of protein kinase C in NIH3T3 cells
โ Scribed by Yoon-Young Chang; Soo-Jung Kim; Tae-Kyu Park; Shin-Sung Kang; Mahn Joon Ha; J. Fredric Mushinski; Jang-Soo Chun
- Book ID
- 111742857
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 482 KB
- Volume
- 45
- Category
- Article
- ISSN
- 1521-6543
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## Abstract Protein kinase C epsilon is an oncogenic, actin nucleating protein that coordinately regulates changes in cell growth and shape. Cells constitutively expressing PKCฯต spontaneously acquire a polarized morphology and extend long cellular membrane protrusions. Here we report that the regul