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Modulation of lysosomal enzyme levels in cultured cells: Effects of alterations in cell density, balanced growth, and endocytosis

✍ Scribed by Jerry Kaplan

Book ID
115703586
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
916 KB
Volume
187
Category
Article
ISSN
0003-9861

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## Abstract Tay‐Sachs disease and normal fetal cerebellar cells were maintained in culture for up to four weeks. Elevated levels of the lysosomal enzymes hexosaminidase B, β‐galactosidase, and acid phosphatase were observed in the Tay‐Sachs cells in long term cultures although elevated lysosomal en