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Modulation of keratan sulfate synthesis on lumican by the action of cytokines on human articular chondrocytes

✍ Scribed by Lee I. Melching; Peter J. Roughley


Book ID
117640723
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
324 KB
Volume
18
Category
Article
ISSN
0945-053X

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✍ Zhao-Ping Lum; Brian E. Hakala; John S. Mort; Anneliese D. Recklies πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 741 KB

The effects of IL-1 p and TGF-P on the biosynthesis of extracellular matrix structural components relative to the metalloproteinases and their inhibitor TlMPl in human articular chondrocytes were investigated. It has been proposed that TGFp, acting as a positive regulator of matrix accretion, can co