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Modulation of innate immune-related pathways in nicotine-treated SH-SY5Y cells

✍ Scribed by Wen-Yan Cui, Ju Wang, Jinxue Wei, Junran Cao, Sulie L. Chang, Jun Gu…

Book ID: 120920392
Publisher: Springer
Year: 2011
Tongue: English
Weight: 456 KB
Volume: 43
Category: Article
ISSN: 0939-4451
DOI: 10.1007/s00726-011-1171-0

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## Abstract Clusterin (apolipoprotein J) is a highly conserved, multifunctional, vertebrate glycoprotein. Several isoforms of clusterin have been described including the predominant secreted isoform (sCLU) and several nuclear isoforms (nCLU) associated with cell death. sCLU has been shown to bind a