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Modulation of Fas-Ligand (Fas-L) on human microglial cells: an in vitro study

✍ Scribed by S Frigerio; V Silei; E Ciusani; G Massa; G.M Lauro; A Salmaggi


Book ID
114139009
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
542 KB
Volume
105
Category
Article
ISSN
0165-5728

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Treatment of human amniotic epithelial (HAE) cells with anti‐Fas monoclonal antibody (CH 11) at 100ng/ml or 1ΞΌg/ml for 12 or 24h increased necrotic cell death. Apoptotic cell death induced by this antibody was significantly increased, although far fewer cells underwent apoptosis, as determined by th