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Modulation of experimental allergic neuritis in rats by in vivo treatment with monoclonal anti T cell antibodies

✍ Scribed by Karin Strigård; Tomas Olsson; Per Larsson; Rikard Holmdahl; Lars Klareskog


Book ID
118930538
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
685 KB
Volume
83
Category
Article
ISSN
0022-510X

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## Abstract The anti‐pan T cell monoclonal antibody OKT3 was administered daily for 2 weeks in four human renal allograft recipients. The antibody induced a dramatic and immediate depletion of peripheral T cells followed by an __in vivo__ antigenic modulation of the OKT3‐defined membrane antigen: a