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Modulation of estrogen receptor transactivation and estrogen-induced gene expression by ormeloxifene—A triphenylethylene derivative

✍ Scribed by Chellakkan S. Blesson; Smita Awasthi; Geetika Kharkwal; Amita Daverey; Anila Dwivedi

Book ID: 116891986
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 781 KB
Volume: 71
Category: Article
ISSN: 0039-128X
DOI: 10.1016/j.steroids.2006.08.001

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## Abstract Estrogen receptor (ER)‐α can signal either via estrogen response element (ERE)‐mediated pathways or via alternate pathways involving protein–protein or membrane signaling. We previously demonstrated that, as compared to wild type (WT) controls, mice expressing a mutant ER‐α lacking the