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Modulation of Elasticity in Functionally Distinct Domains of the Tropomyosin Coiled-Coil

โœ Scribed by Sirish Kaushik Lakkaraju; Wonmuk Hwang

Book ID
107620660
Publisher
Springer
Year
2009
Tongue
English
Weight
544 KB
Volume
2
Category
Article
ISSN
1865-5025

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## Synopsis CD experiments are reported for several coiled-coil species in the tyrosine/disulfide (-250-350-nm) region. Intact noncross-linked tropomyosin ( -3ยฐC) shows a negative nonsymmetric band maximal at 280 nm. This spectrum is the sum over six tyrosines/chain, and has conformational signifi

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## SYNOPSIS Measurements are presented on the time course of chain exchange among two-chain ahelical coiled coils of rabbit tropomyosin. All experiments are in a regime (temperature, protein concentration) in which coiled-coil dimers are the predominant species. Self-exchange in rue-tropomyosin wa