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Modulation of cis-diamminedichloroplatinum (II) accumulation and cytotoxicity by spermine in sensitive and resistant human ovarian carcinoma cells

✍ Scribed by G. Marverti; P.A. Andrews; G. Piccinini; S. Ghiaroni; D. Barbieri; M.S. Moruzzi

Book ID
117663704
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
771 KB
Volume
33
Category
Article
ISSN
0959-8049

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Background. Previous studies have demonstrated that tumor cells have different degrees of sensitivity and resistance to various cytotoxic agents. The acquisition of drug resistance is a major concern in cancer treatment. The current study investigates the cytotoxic effect of cisdiamminedichloroplati