✦ LIBER ✦

Modulation of Catalyst Reactivity for the Chemoselective Hydrogenation of a Functionalized Nitroarene: Preparation of a Key Intermediate in the Synthesis of ( R , R )-Formoterol Tartrate

✍ Scribed by Wilkinson, H. Scott; Hett, Robert; Tanoury, Gerald J.; Senanayake, Chris H.; Wald, Stephen A.

Book ID: 120170042
Publisher: American Chemical Society
Year: 2000
Tongue: English
Weight: 76 KB
Volume: 4
Category: Article
ISSN: 1083-6160
DOI: 10.1021/op000287k

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Improved Process for Preparation of (3 R

Improved Process for Preparation of (3 R ,4 R )-3-(3,4-Dimethyl-4-piperidinyl)phenol, A Key Intermediate for the Synthesis of Alvimopan

✍ Reddy, Beeravalli Ramalinga; Reddy, Kikkuru Srirami; Dubey, Manoj Kumar; Kumari, 📂 Article 📅 2013 🏛 American Chemical Society 🌐 English ⚖ 573 KB

Studies on the preparation of the “Ziegl

Studies on the preparation of the “Ziegler intermediate”, a key intermediate in the total synthesis of forskolin

✍ M. Leclaire; R. Levet; F. Péricaud; L. Ricard; J.Y. Lallemand 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 885 KB

Preparation of the "Ziegler key intermediate" 2from lactone 3, readily obtained from hydroxy-O-ionone, was studied. In a first exploratory approach, lactones 11 and 13 were obtained but further transformations aimed at setting the ring junction were unsuccessful due to unexpected rearrangements. Thr

Diethylanilineborane: A Practical, Safe,

Diethylanilineborane: A Practical, Safe, and Consistent-Quality Borane Source for the Large-Scale Enantioselective Reduction of a Ketone Intermediate in the Synthesis of ( R , R )-Formoterol

✍ Wilkinson, H. Scott; Tanoury, Gerald J.; Wald, Stephen A.; Senanayake, Chris H. 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 35 KB

A short, stereoselective synthesis of (3

A short, stereoselective synthesis of (3R,4R)-4-acetoxy-3-[(R)-1′((t-butyldimethylsilyl)oxy) ethyl]-2-azetidinone, key intermediate for the preparation of carbapenem antibiotics

✍ Franco Cozzi; Rita Annunziata; Mauro Cinquini; Laura Poletti; Alcide Perboni; Br 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 63 KB

A short stereoselective synthesis of the acetoxy azetidinone (1), an important precursor of several biologically active ␤-lactam antibiotics, has been accomplished in seven steps and 32.8% overall yield from the easily available and inexpensive (R) ethyl 3-hydroxybutanoate.

ChemInform Abstract: Studies on the Prep

ChemInform Abstract: Studies on the Preparation of the “Ziegler Intermediate”, a Key Intermediate in the Total Synthesis of Forskolin.

✍ M. LECLAIRE; R. LEVET; F. PERICAUD; L. RICARD; J. Y. LALLEMAND 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

Synthesis of enantiopure (R)-2-(4-methox

Synthesis of enantiopure (R)-2-(4-methoxy-3-(3-methoxypropoxy)-benzyl)-3-methylbutanoic acid—a key intermediate for the preparation of Aliskiren

✍ Natalia Andrushko; Vasyl Andrushko; Thomas Thyrann; Gerd König; Armin Börner 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 184 KB

The enantioselective hydrogenation of (E)-2-(4-methoxy-3-(3-methoxypropoxy)-benzylidene)-3-methylbutanoic acid (1) to (R)-2-(4-methoxy-3-(3-methoxypropoxy)-benzyl)-3-methylbutanoic acid (2)-a key intermediate in the synthesis of the pharmacologically important renin inhibitor Aliskiren-is described.