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Modulation of Binding of DNA to the C-Terminal Domain of p53 by Acetylation

✍ Scribed by Assaf Friedler; Dmitry B. Veprintsev; Stefan M.V. Freund; Karoly I. von Glos; Alan R. Fersht


Book ID
113918409
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
250 KB
Volume
13
Category
Article
ISSN
0969-2126

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## Abstract The ubiquitin‐like molecule, SUMO‐1, a small protein essential for a variety of biological processes, is covalently conjugated to many intracellular proteins, especially to regulatory components of the transcriptional machinery, such as histones and transcription factors. Sumoylation pr