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Modulation of alkaline phosphatase activity in KB cells by hyperosmolality and prednisolone: Effect on enzyme inhibition by phosphate

✍ Scribed by Fritz Herz

Book ID
112796513
Publisher
Society for In Vitro Biology
Year
1974
Tongue
English
Weight
477 KB
Volume
10
Category
Article
ISSN
1475-2689

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The inhibition by xanthine phosphodieste
The inhibition by xanthine phosphodiesterase inhibitors of the induction of alkaline phosphatase activity in HeLa cells: Relationship of enzyme activity to cyclic AMP concentrations
✍ Walker Wharton; Barry Goz πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 681 KB

## Abstract The three xanthine derivatives, caffeine, theophylline and 3‐isobutyl‐1‐methyl‐xanthine (IBMX) produced dose‐dependent increases in cyclic AMP concentrations in HeLa cells after long term treatment. Only IBMX produced increases over the first 60 minutes, with a peak of approximately 5‐f