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Modulation of aflatoxin B1 biotransformation by β-naphthoflavone in isolated rabbit lung cells

✍ Scribed by Sue H. Im; Michael W. Bolt; Richard K. Stewart; Thomas E. Massey

Book ID
105871440
Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
454 KB
Volume
71
Category
Article
ISSN
0340-5761

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Aflatoxin B 1 (AFB 1 ) is a clastogen that causes cellular damage by covalent modification of nucleic acids. In this investigation, male rats were injected i.p. with AFB 1 (8 mg/kg b.w.) in DMSO and the same dose of AFB 1 was also administered intratracheally (i.t.) to the animals separately. The an