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Modulation of 5-fluorouracil metabolism by thymidine: In vivo and in vitro studies on RNA-directed effects in rat liver and hepatoma

✍ Scribed by Claes Engelbrecht; Inga Ljungquist; Lillemor Lewan; Torsten Yngner


Book ID
115777686
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
656 KB
Volume
33
Category
Article
ISSN
0006-2952

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Thymidine-modulated 5-fluorouracil metab
✍ Paul E. Sijens; Thian C. Ng πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 810 KB

19F Magnetic resonance spectroscopy was used to study the impact of the biochemical modulator thymidine (TdR) on the 5-fluorouracil (5FU) metabolism in the livers and radiation-induced fibrosarcoma (RIF-1) tumors of 5FU-treated C3H mice. The liver spectra measured after administration of 5FU (65 or