Thymidine phosphorylase (dThdPase) is an essential enzyme for the activation of the oral cytostatic drugs capecitabine (N 4 -pentyloxycarbonyl-5Ј-deoxy-5-fluorocytidine, Xeloda ) and its intermediate metabolite doxifluridine [5Ј-deoxy-5-fluorouridine (5Ј-dFUrd, Furtulon )] to 5-fluorouracil (5-FUra)
✦ LIBER ✦
Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: In vitro and In vivo study
✍ Scribed by Alexre Evrard; Pierre Cuq; Bruno Robert; Laurence Vian; André Pèlegrin; Jean-Paul Cano
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- French
- Weight
- 428 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0020-7136
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