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Modulation by dopamine of [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3h]btcp, a phencyclidine derivative) binding to the dopamine uptake complex

✍ Scribed by T. Maurice; G. Barbanel; J.-M. Kamenka; J. Vignon


Book ID
118956431
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
832 KB
Volume
30
Category
Article
ISSN
0028-3908

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High specific activity [3H]BTCP, a radioligand for the dopaminereuptake complex was synthesized in 7-steps starting with the readily available starting materials, cyclohexane-l,4-dione monoethylene ketal and benzo[b]thiophene; the tritium label was introduced in the final step on the 3-and 4-positio