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Modulating sensitivity to drug-induced apoptosis: the future for chemotherapy?

✍ Scribed by Guy Makin, Caroline Dive


Book ID
120700765
Publisher
BioMed Central
Year
2001
Tongue
English
Weight
172 KB
Volume
3
Category
Article
ISSN
1465-5411

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Resistance to apoptosis plays an important role in malignancies that are refractory to chemotherapy treatment. Recently we have shown that the expression of bax-a, a death-promoting member of the bcl-2 family, is down-regulated in breast cancer and have provided evidence that low bax expression migh