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Modifiers of epigenetic reprogramming show paternal effects in the mouse

✍ Scribed by Chong, Suyinn; Vickaryous, Nicola; Ashe, Alyson; Zamudio, Natasha; Youngson, Neil; Hemley, Sarah; Stopka, Tomas; Skoultchi, Arthur; Matthews, Jacqui; Scott, Hamish S

Book ID
109919554
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
595 KB
Volume
39
Category
Article
ISSN
1061-4036

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## Abstract Summary: Genome‐wide epigenetic reprogramming by demethylation occurs in early mouse embryos and primordial germ cells. In early embryos many single‐copy sequences become demethylated both by active and passive demethylation, whereas imprinted gene methylation remains unaffected. In pri