Modified cyclodextrins as stationary phases for capillary GC: Consequences of dilution in polysiloxanes
✍ Scribed by Schmarr, Hans-Georg ;Mosandl, Armin ;Neukom, Hans-Peter ;Grob, Konrad
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 487 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0935-6304
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## Abstract The influence of different polysiloxane solvents on the efficiency and stereoselectivity of columns coated with mixtures of heptakis(2,3‐di‐O‐methyl‐6‐O‐__tert__‐butyldimethylsilyl)‐β‐cyclodextrin (DIME‐6‐TBDMS‐β‐CD) and the polysiloxanes was investigated. In the case of DIME‐6‐TBDMS‐β‐
## Abstract __tert__‐Butyldimethylsilylated cyclodextrin derivatives dissolved in polysiloxanes were shown to be versatile chiral stationary phases for the differentiation of important chiral food and flavor ingredients and chiral acids of biochemical and pharmaceutical interest.
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Separation factors and thermodynamic data for the separation of various chiral analytes on different 6-TBDMS-derivatized y( p )-cyclodextrin-phases were collected and discussed. Modifying the alkyl chain length of the substituents in position 2, and 3 of the cyclodextrin molecule or changing from p