Solid phase synthesis of benzothiazole a
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Xian Huang; Jing Tang
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Article
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2003
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Elsevier Science
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French
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A new method for the solid phase synthesis of benzothiazoles and 2-arylamino-3-carboxyl-4-hydroxy-5-arylthiophenes is described. Resin bound cyclic malonic acid ester was reacted with aryl isothiocyanates and then with bromine or a-bromoketones, followed by treatment with perchloric acid or sodium m